Assembly and Positioning of the Oocyte Meiotic Spindle
نویسندگان
چکیده
منابع مشابه
Oocyte Meiotic Spindle Assembly and Function.
Gametogenesis in animal oocytes reduces the diploid genome content of germline precursors to a haploid state in gametes by discarding ¾ of the duplicated chromosomes through a sequence of two meiotic cell divisions called meiosis I and II. The assembly of the microtubule-based spindle structure that mediates this reduction in genome content remains poorly understood compared to our knowledge of...
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Female germ cell meiotic divisions are typically asymmetric, giving rise to two daughter cells with different sizes. Spindle movements including spindle migration from the oocyte center to the cortex and spindle rotation from parallel to perpendicular (typically in the mouse) at the cortex are crucial for these asymmetric divisions and therefore are crucial for gamete production. Different regu...
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ژورنال
عنوان ژورنال: Annual Review of Cell and Developmental Biology
سال: 2018
ISSN: 1081-0706,1530-8995
DOI: 10.1146/annurev-cellbio-100616-060553